My friend has the new Vette, the steering wheel is flat on top and bottom. He thought it looked cool. Now that he has put some miles on the car, he hates it. As he turns the wheel and reaches for the wheel as he is turning it, he suddenly finds there is nothing there to grab as he has hit 'a flat spot'. I would think the yoke would be worse.
I think that is most significant problem, 90 degree turns of the car (not the wheel), especially in local driving, or any other maneuver (maybe some parking) that causes more than a 90 degree turn of the wheel. I think it would be fine otherwise (and fun) for things like highway driving, or entering or exiting the highway with less than 90 degree steering wheel motion.
In aircraft, the yoke is turned in either rotational direction to enter the desired angle of bank, but then mostly returned to the level position once in the bank. There are exceptions. Most people have probably seen pilots wrestling a yoke in severe crosswind or gust conditions. In some jets, instead of crabbing (angling away from the center line of the runway), it is okay to slip to maintain runway centerline, letting the slip out on touchdown, and there too the yoke might be at some angle for a while, but never near 90 degrees. So in aircraft, where the yoke is at home, there is no use at 90 degrees or beyond.
It is the more than 90 degree motion of the steering wheel, and even more than one turn in many cases, that makes a yoke mostly unsuitable for regular driving, especially driving local roads and parking.
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($34,500 does not include state tax and fees; the tax is calculated here after any trade in credit)
